What is pemphigus vulgaris? Pemphigus vulgaris is caused by immunoglobulin G (IgG) autoantibodies which bind to a protein called desmoglein 3. As clinical features, there are thin-walled flaccid blisters filled with clear fluid causing itchy and painful erosions. Darken erythematous crusted patch with some areas of blister and erosions can be seen on the back […]